Volume 74, Issue 9 p. 1361-1367
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Effect of Non-Surgical Periodontal Therapy on Glycemic Control in Patients with Type 2 Diabetes Mellitus

Dr. Débora C. Rodrigues

Dr. Débora C. Rodrigues

Department of Surgery and Periodontology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

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Mário Taba Jr.

Corresponding Author

Mário Taba Jr.

Department of Surgery and Periodontology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

Correspondence: Dr. Mário Taba Jr., Faculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Av do Café s/n, 14040-904, Ribeirão Preto, SP, Brazil. E-mail: [email protected].Search for more papers by this author
Arthur B. Novaes Jr.

Arthur B. Novaes Jr.

Department of Surgery and Periodontology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

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Sérgio L.S. Souza

Sérgio L.S. Souza

Department of Surgery and Periodontology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

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Márcio F.M. Grisi

Márcio F.M. Grisi

Department of Surgery and Periodontology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

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First published: 01 September 2003
Citations: 158

Abstract

Background: The literature suggests that an alteration in glucose metabolism occurs as a result of antibacterial periodontal therapy. The objective of this study was to monitor the effect of non-surgical periodontal therapy on glycemic control in patients with type 2 diabetes mellitus (DM).

Methods: Thirty type 2 DM subjects with periodontitis were randomly divided into two groups. Group 1 (G1), 15 subjects, received one-stage full-mouth scaling and root planing (FMSRP) plus amoxicillin/clavulanic acid 875 mg; group 2 (G2), 15 patients, received only FMSRP. At baseline and after 3 months, the glycated hemoglobin (HbA1c) values, fasting glucose, and clinical parameters (with computerized probing and individualized acrylic stents) were recorded. Following therapy, the subjects were enrolled in a 2-week interval maintenance program for 3 months.

Results: After treatment, both groups showed clinical improvements. A probing depth (PD) reduction of 0.8 ± 0.6 mm (P <0.05) occurred in G1 and 0.9 ± 0.4 mm in G2 (P <0.05), but there were no significant changes in attachment level. Treatment reduced the HbA1c values after the 3-month observation period in both groups; however, the reduction in HbA1c values for the G2 group was statistically significant, but not for the G1 group. The changes in fasting glucose levels were not significant for either group.

Conclusions: Periodontal therapy improved glycemic control in patients with type 2 DM in both groups; however, the reduction in HbA1c values reached statistical significance only in the group receiving scaling and root planing alone. J Periodontol 2003;74:1361-1367.